Introduction to Classical Hematology
Acute Monocytic Leukemia (AML-M5)
Peripheral smear from a 90-year-old female who presented to the hospital with confusion and shortness of breath and was found to have a significantly elevated white blood cell count to 140 K/UL, hemoglobin 9.1g/dL, and platelets 52 K Her differential showed 135…
Blood Transfusion Thresholds
Spur Cell Hemolytic Anemia
Peripheral smear of a patient with a history of prostate cancer and admitted with liver failure and signs of liver disease. His laboratory workup showed signs consistent with hemolysis and his smear seen above showed marked red blood cell abnormalities. Although the…
PACIFIC AF Trial (2022)
The Pacific AF trial was published in The Lancet in April 2022. It was a phase 2 randomized controlled trial performed at multiple centers in 14 countries including European, Canada, and Japan. The study compared the novel oral small molecule activated coagulation…