Prognostic Clinical Tools (Risk Stratification) in Lymphomas
An overview of the most frequently used stratification tools in diffuse large B-cell lymphoma (IPI), follicular lymphoma (FLIPI), and mantle cell lymphoma (MIPI)
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Inherited Bone Marrow Failure Syndromes (IBMFS)
An overview of the inherited bone marrow failure syndromes (IBMFs), when to suspect them, and a brief description of the most common IBMFs
Low-Dose vs Full-Dose Apixaban in VTE: What Does AMPLIFY-EXT Trial Tell Us?
A short review of the AMPLIFY-EXT trial which evaluated the use of apixaban at 2.5 mg BID and 5 mg BID vs placebo for the prophylaxis of VTE after an initial course of anticoagulation
Vitamin B12 Deficiency
Review of the most important aspects to consider for the diagnosis and management of vitamin B12 deficiency.
Anemia of Inflammation/Anemia of Chronic Disease
Review of anemia of inflammation including its definition, pathophysiology, the role of hepcidin, diagnosis, and management. A special focus is given at the differential between anemia of inflammation and iron deficiency
Methemoglobinemia
A summary of methemoglobinemia and review its definition, causes, clinical manifestations, and management of both acquired and congenital forms
Less Common Hemoglobin Variants (D, E, O, H)
In this post, we explore the less common hemoglobin variants—D, E, O, and H—highlighting their key characteristics and clinical significance. Additionally, we provide a brief overview of hydrops fetalis
Disorders of Hemoglobin C
We describe the hemoglobin C variants, its clinical manifestations, particularly in hemoglobin C disease, Hb sickle disease, and the management of these conditions
Management of Sickle Cell Disease/Sickle Cell Anemia (SCD/SCA)
Management of sickle cell disease including acute complications (vasoocclusive events, acute chest syndrome, stroke, and others), and long term management including medications, blood products, stem cell transplant, and gene therapy
Sickle Cell Disease (SCD) and Hemoglobin S Disorders
An overview of hemoglobin S disorders including their definitions, epidemiology, classification, diagnosis, and prognosis of these conditions. An introduction to a future review of the management of sickle cell disease
Management of Thalassemias
A summary of the management of thalassemias with emphasis on the management of anemia with transfusion support, iron overload, medications such as luspatercept, and advanced treatments such as stem cell and gene therapy
Overview of Thalassemias
An overview of thalassemias including their definition, classification, and description of the most common thalassemias. We hope to help you understand the differences between alpha and beta thalassemias better!
Iron Deficiency Anemia (IDA)
A review of iron deficiency with and without anemia and their clinical manifestations, diagnosis, management, and monitoring of response. A key topic in hematology!
Causes and Classification of Anemias
Explore the causes and classifications of anemias, from microcytic, normocytic, and macrocytic types. A classification to help you understand the big picture of all anemias!
Overview of Red Blood Cells
An introduction to red blood cells, their anatomy, function, erythropoiesis, RBC lifespan, and classification of red blood cell disorders (anemias and polycythemias)
