Review of anemia of inflammation including its definition, pathophysiology, the role of hepcidin, diagnosis, and management. A special focus is given at the differential between anemia of inflammation and iron deficiency
In this post, we explore the less common hemoglobin variants—D, E, O, and H—highlighting their key characteristics and clinical significance. Additionally, we provide a brief overview of hydrops fetalis
We describe the hemoglobin C variants, its clinical manifestations, particularly in hemoglobin C disease, Hb sickle disease, and the management of these conditions
Management of sickle cell disease including acute complications (vasoocclusive events, acute chest syndrome, stroke, and others), and long term management including medications, blood products, stem cell transplant, and gene therapy
An overview of hemoglobin S disorders including their definitions, epidemiology, classification, diagnosis, and prognosis of these conditions. An introduction to a future review of the management of sickle cell disease
A summary of the management of thalassemias with emphasis on the management of anemia with transfusion support, iron overload, medications such as luspatercept, and advanced treatments such as stem cell and gene therapy
An overview of thalassemias including their definition, classification, and description of the most common thalassemias. We hope to help you understand the differences between alpha and beta thalassemias better!
A review of iron deficiency with and without anemia and their clinical manifestations, diagnosis, management, and monitoring of response. A key topic in hematology!
Explore the causes and classifications of anemias, from microcytic, normocytic, and macrocytic types. A classification to help you understand the big picture of all anemias!
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